NEWEST 2ml (Plenyhage Medium) 2% (10mg) PN-HPT – Professional Dual-Action Polynucleotide + HA Injectable
NEWEST 2ml is a patented sterile injectable gel from Mastelli that combines 10 mg/ml PN-HPT (High Purification Technology polynucleotides) with 10 mg/ml non-cross-linked hyaluronic acid and mannitol. Designed for intradermal use on the face, neck and décolletage, it delivers simultaneous regenerative stimulation and deep hydration to improve skin quality in mature, dehydrated or damaged skin. Order authentic NEWEST 2ml (Plenyhage Medium equivalent) today for reliable professional results.
Why Clinics Choose NEWEST 2ml
When you buy NEWEST 2ml, you select Mastelli’s exclusive dual-action formula that pairs the fibroblast-stimulating benefits of highly purified polynucleotides with the immediate hydrating effect of non-cross-linked HA, stabilised by mannitol. This combination supports collagen and elastin production while enhancing moisture retention, making it particularly effective for acne scarring, photoageing, roughness and significant signs of skin damage.
NEWEST is indicated for biorevitalisation of the face, neck and décolletage, with suggested use on mature and dehydrated skin requiring both regenerative and hydrating support.
Key Benefits of NEWEST 2ml (10 mg/ml PN-HPT + HA)
- 10 mg/ml PN-HPT highly purified polynucleotides for tissue regeneration
- 10 mg/ml non-cross-linked hyaluronic acid for intense hydration
- Mannitol to help protect and prolong the effects of HA
- Improves skin elasticity, brightness and overall quality
- Helps reduce the appearance of wrinkles, roughness and scarring
- Suitable for face, neck and décolletage
- Convenient 2 ml pre-filled syringe with 30G needles
Clinical observations associated with the product report meaningful improvements in elasticity, brightness and reduction of wrinkles and rough skin after a course of treatments.
Treatment Protocol and Professional Use
NEWEST is administered by intradermal injection. Recommended protocols typically include one session every 14–21 days: three sessions for younger patients and four sessions for more advanced signs of ageing. Only licensed medical professionals trained in injectable techniques should perform the treatment under sterile conditions.
How to Select Genuine NEWEST 2ml
When you buy NEWEST 2ml, source from authorised professional suppliers that guarantee original Mastelli packaging, batch and expiry traceability, and correct storage. Confirm the authentic 2 ml pre-filled syringe containing 10 mg/ml PN-HPT® + 10 mg/ml non-cross-linked HA + mannitol (often supplied with two 30G ½ needles).
Order Authentic NEWEST 2ml (Plenyhage Medium) 2% (10mg) PN-HPT Today
Equip your clinic with Mastelli’s patented polynucleotide + hyaluronic acid dual-action injectable for comprehensive skin regeneration and hydration. NEWEST 2ml delivers progressive improvement in elasticity, brightness and texture with professional results. Order genuine product now and expand your advanced biorevitalisation offerings. Fast professional shipping available — buy NEWEST 2ml today.
Frequently Asked Questions
What is NEWEST 2ml used for? It is used for intradermal biorevitalisation of the face, neck and décolletage to improve elasticity, brightness, hydration and the appearance of wrinkles, roughness, acne scarring and signs of ageing or skin damage.
What are the main active ingredients? Each 2 ml syringe contains 10 mg/ml PN-HPT (highly purified polynucleotides), 10 mg/ml non-cross-linked hyaluronic acid and mannitol.
How does it differ from pure polynucleotide products such as Plinest? NEWEST combines PN-HPT with non-cross-linked HA and mannitol for simultaneous regenerative and hydrating effects, whereas pure PN products focus primarily on tissue stimulation without the added HA component.
How many sessions are typically needed? Younger patients: one session every 14–21 days for a total of 3 sessions. Advanced skin ageing: the same interval for a total of 4 sessions. Maintenance is determined by the practitioner.
Who can buy and inject NEWEST 2ml? This product is intended exclusively for use by licensed medical professionals in clinical settings. It is not for self-administration.
Is it related to Plenhyage Medium? NEWEST is frequently positioned as a Mastelli polynucleotide + HA option in the same category as medium-strength regenerative injectables such as Plenhyage Medium, offering a dual-action alternative.
This content is for informational purposes only and is intended for licensed medical professionals. NEWEST is a medical device for professional use. Always follow the official instructions for use, local regulations and clinical guidelines. Individual results may vary.

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